From Lisa

Contents 1 Contact 2 Teaching 3 Research topics 4 Publications 4.1 Thesis 5 Project and stage

Contact

odebeirATulb.ac.be

tel.:++32.2.650.22.95 fax:++32.2.650.22.98

ULB - LISA CP165/57

50, Av. F.Roosevelt

1050 Bruxelles

Belgium

Teaching

Professor for the following course:

• BIME-H-404 Introduction to medical imaging
• INFO-H-500 Image acquisition and processing
• INFO-H-501 Pattern recognition and image analysis
• INFO-H-503 Animation and virtual reality
• MEDI-H-501 Computer Assisted Medical Interventions
• PROJ-H-401 Medical imaging project

Research topics

Biomedical Image Analysis cell biology and Cellular_imaging Quantitative_immunohistochemical_analysis Melanoma diagnosis aid		Industrial applications Wood analysis Document analysis
Remote Sensing image analysis Remote_sensing Machine Learning MARCH : Multi-classifier systems (MCS)		Others Animal and Veterinary Histological Atlas [1]

Publications

Papers

Unay, Devrim, Gosselin, Bernard, Leemans, Vinent, Destain, Marie-France, Debeir, Olivier,
Automatic Grading of Bi-Colored Apples by Multispectral Machine Vision
Computers and Electronics in Agriculture, Vol. 75, 1, pp. 204-212, Jan 2011
Bibtex

Bibtex : devrim11a

Adanja, I., Megalizzi, V., Debeir, O., Decaestecker, C.,
A new method to address unmet needs for extracting individual cell migration features from a large number of cells embedded in 3D volumes
PLoS ONE, Vol. 6, pp. e22263, 2011
Bibtex

Bibtex : pmid21789244

Letort V., Fouliard S., Letort G., Adanja I., Kumasaka M., Gallagher S., Debeir O., Larue L., Xavier F.,
Quantitative Analysis of Melanocyte Migration in vitro Based on Automated Cell Tracking under Phase Contrast Microscopy Considering the Combined Influence of Cell Division and Cell-Matrix Interactions
Mathematical Modelling of Natural Phenomena, Vol. 5, 1, pp. 4-33, Feb 2010
Bibtex

Bibtex : letort10a
Abstract : The aim of this study was to describe and analyze the regulation and spatio-temporal dynamics of melanocyte migration in vitro and its coupling to cell division and interaction with the matrix. The melanocyte lineage is particularly interesting because it is involved in both embryonic development and oncogenesis/metastasis (melanoma). Biological experiments were performed on two melanocyte cell lines established from wild-type and β-catenin-transgenic mice (bcat*). The multi-functional β-catenin molecule is known to be able to regulate the transcription of various genes involved in cell proliferation and migration, particularly in the melanocyte lineage. We also investigated fibronectin, an extra-cellular matrix protein that binds integrins, thereby providing adhesion points for cells and encouraging migration. As the migration of individual cells were followed, automated methods were required for processing the large amount of data generated by the time-lapse video-microscopy. A model-based approach for automated cell tracking was evaluated on a sample by comparison with manual tracking. This method was found reliable in studying overall cell behaviour. Its application to all the observed sequences provided insight into the factors affecting melanocyte migration in vitro: melanocytes of mutated form of β-catenin showed higher division rates and no contact inhibition of growth was induced by the resulting increase in cell density. However, cell density limited the amplitude of cell displacements, although their motility was less affected. The high fibronectin concentration bound to substratum promoted cell migration and motility, the effect being more intense for wild-type cells than for cells with β-catenin over-expression. During the division process, cell migration speed increased rapidly then decreased slowly. Analyses of such data is expected to lead both to biological answers and to a framework for a better modeling processes in the future.

Ivan Adanja, Olivier Debeir, Véronique Mégalizzi, Robert Kiss, Nadine Warzée, Christine Decaestecker,
Automated tracking of unmarked cells migrating in three-dimensional matrices applied to anti-cancer drug screening
Experimental Cell Research, Vol. 316, 2, pp. 181 - 193, 2010
Bibtex

Bibtex : adanja10

Wauthoz N., Deleuze Ph., Hecq J., Roland I., Saussez S., Adanja I., Debeir O., Decaestecker C., Mathieu V., Kiss R., Amighi K.,
In Vivo Assessment of Temozolomide Local Delivery for Lung Cancer Inhalation Therapy
European Journal of Pharmaceutical Sciences, Vol. 39, pp. 402-411, 2010
Bibtex

Bibtex : wauthoz10a

Megalizzi, V., Decaestecker, C., Debeir, O., Spiegl-Kreinecker, S., Berger, W., Lefranc, F., Kast, R. E., Kiss, R.,
Screening of anti-glioma effects induced by sigma-1 receptor ligands: Potential new use for old anti-psychiatric medicines
Eur. J. Cancer, Vol. 45, pp. 2893-905, Nov 2009
Bibtex

Bibtex : mégalizzi09
Abstract : The prognosis of glioblastoma (GBM) remains poor. Diffuse invasion of distant brain tissue by migrating cells from the primary tumour mass has already occurred at time of diagnosis. Anti-cancer effects of a selective sigma-1 agonist, 4-(N-benzylpiperidin-4-yl)-4-iodobenzamide (4-IBP), in glioblastoma were shown previously, leading to the present work where the effects on glioblastoma cells of 17 agonists or antagonists of sigma-1 receptors were studied, including currently marketed drugs fluvoxamine, dextromethorphan, donepezil, memantine and haloperidol. We first showed that established GBM cell lines, primary cultures and surgical specimens express sigma-1 receptors. In vitro analyses then focused on anti-proliferation and anti-migratory effects on human glioblastoma cell lines using quantitative videomicroscopy analyses. These cell monitoring assays revealed specific impacts on the mitotic cell process. Using an aggressive glioma model orthotopically grafted into the brains of immunocompromised mice, we showed that combining donepezil and temozolomide gave additive benefit in terms of long survivors as compared to temozolomide or donepezil alone. Clinical study is planned if further rodent dose-ranging studies of donepezil with temozolomide continue to show evidence of benefit in this model.

Leyman, S., Sidani, M., Ritsma, L., Waterschoot, D., Eddy, R., Dewitte, D., Debeir, O., Decaestecker, C., Vandekerckhove, J., van Rheenen, J., Ampe, C., Condeelis, J., Van Troys, M.,
Unbalancing the PI(4,5)P2-Cofilin Interaction Impairs Cell Steering
Mol. Biol. Cell, Vol. 20, pp. 4509-23, Nov 2009
Bibtex

Bibtex : leyman09

Decaestecker, C., Moles Lopez, X., D'Haene, N., Roland, I., Guendouz, S., Duponchelle, C., Berton, A., Debeir, O., Salmon, I.,
Requirements for the valid quantification of immunostains on tissue microarray materials using image analysis
Proteomics, Vol. 8, pp. 1739--1750, Aug 2009
Bibtex

Bibtex : decaes09
Abstract : Antibody-based proteomics applied to tissue microarray (TMA) technology provides a very efficient means of visualizing and locating antigen expression in large collections of normal and pathological tissue samples. To characterize antigen expression on TMAs, the use of image analysis methods avoids the effects of human subjectivity evidenced in manual microscopical analysis. Thus, these methods have the potential to significantly enhance both precision and reproducibility. Although some commercial systems include tools for the quantitative evaluation of immunohistochemistry-stained images, there exists no clear agreement on best practices to allow for correct and reproducible quantification results. Our study focuses on practical aspects regarding (i) image acquisition (ii) segmentation of staining and counterstaining areas and (iii) extraction of quantitative features. We illustrate our findings using a commercial system to quantify different immunohistochemistry markers targeting proteins with different expression patterns (cytoplasmic, nuclear or membranous) in colon cancer or brain tumor TMAs. Our investigations led us to identify several steps that we consider essential for standardizing computer-assisted immunostaining quantification experiments. In addition, we propose a data normalization process based on reference materials to be able to compare measurements between studies involving different TMAs. In conclusion, we recommend certain critical prerequisites that commercial or in-house systems should satisfy in order to permit valid immunostaining quantification.

N. Warzée, M. Groenen, J. Rosoux, O. Debeir, R. Ercek, C. Reichling,
Numérisation 3D de la grotte d'El Castillo (Puento Viesgo)
Ausonius Editions / collection archéovision, Vol. 3, pp. 221-229, 2009
Bibtex

Bibtex : warzée09a

Debeir O., Mégalizzi V., Warzée N., Kiss R., Decaestecker C.,
Videomicroscopic extraction of specific information on cell proliferation and migration in vitro
Exp. Cell Res., Vol. 314, pp. 2985-2998, Oct 2008
Bibtex

Bibtex : debeir08

Le Mercier M., Lefranc F., Mijatovic T., Debeir O., Haibe-Kains B., Bontempi G., Decaestecker C., Kiss R., Mathieu V.,
Evidence of galectin-1 involvement in glioma chemoresistance
Toxicol Appl Pharmacol, Vol. 229, 2, pp. 172-183, June 2008
Bibtex

Bibtex : lemercier08b

Lefranc F., Mijatovic T., Kondo Y., Sauvage S., Roland I., Debeir O., Krstic D., Vasic V., Gailly Ph., Kondo S., Blanco G., Kiss R.,
TARGETING THE [alpha] 1 SUBUNIT OF THE SODIUM PUMP TO COMBAT GLIOBLASTOMA CELLS. EXPERIMENTAL STUDIES
Neurosurgery, Vol. 62, 1, pp. 221-222, Jan 2008
Bibtex

Bibtex : lefranc08

S. Rorive, A. Berton, N. D'haene, C. N. Takacs, O. Debeir, C. Decaestecker, I. Salmon,
Matrix metalloproteinase-9 interplays with the IGFBP2-IGFII complex to promote cell growth and motility in astrocytomas.
Glia, Vol. 56, 15, pp. 1679-90, 2008
Bibtex

Bibtex : pmid658242

Cammaerts M.C., Vandenbussche A., Debeir O.,
Méthode d'étude de la forme d'une structure microscopique, opaque et solide, appliquée à l'oeil d'une fourmi
Belgian Journal of Entomology, Vol. 10, pp. 67-79, 2008
Bibtex

Bibtex : debeir08a

Rachidi Z., Cammaerts M.C., Debeir O,
Morphometric study of the eye of three species of Myrmica (Formicidae)
Belgian Journal of Entomology, Vol. 10, pp. 81-91, 2008
Bibtex

Bibtex : rachidi08a

Mijatovic T., Van Quaquebeke E., Delest B., Debeir O., Darro F., Kiss R.,
Cardiotonic steroids on the road to anti-cancer therapy
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, Vol. 1776, 1, pp. 32-57, Sept 2007
Bibtex

Bibtex : mijatovic07b

O. Debeir, P. Dunham, L. Engels, T. Leloup, X. Baele, N. Warzée,
High Resolution 3D Acquisition of the Olivier Strebelle's Sculpture "Athletes' Alley in Beijing 2008"
International Review on Computers and Software (IRECOS), Vol. 2, 5, pp. 541-545, Sept 2007
Bibtex

Bibtex : debeir07b

Mégalizzi V., Mathieu V., Mijatovic T., Gailly P., Debeir O., De Neve N., Van Damme M., Bontempi G., Haibe-Kains B., Decaestecker C., Kondo Y., Kiss R., Lefranc F.,
4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs.
Neoplasia, Vol. 9, 5, pp. 358-69, May 2007
Bibtex

Bibtex : megalizzi07

Decaestecker C., Debeir O., Van Ham P., Kiss R.,
Can anti-migratory drugs be screened in vitro? A review of 2D and 3D assays for the quantitative analysis of cell migration.
Med Res Rev, Vol. 27, 2, pp. 149-76, March 2007
Bibtex

Bibtex : decaestecker07r

Servotte S., Camby I., Debeir O., Deroanne C., Lambert C. A., Lapière C. M, Kiss R., Nusgens B., Decaestecker C.,
The In Vitro Influences of Neurotensin on the Motility Characteristics of Human U373 Glioblastoma Cells.
Neuropathology and Applied Neurobiology, Vol. 32, 6, pp. 575-84, Dec 2006
Bibtex

Bibtex : servotte05
Note : accepted for publication 2005

Rorive S., Maris C., Debeir O., Sandras F., Vidaud M., Bieche I., Salmon I., Decaestecker C.,
Exploring the Distinctive Biological Characteristics of Pilocytic and Low-Grade Diffuse Astrocytomas Using Microarray Gene Expression Profiles.
J Neuropathol Exp Neurol., Vol. 65, 8, pp. 794-807, Aug 2006
Bibtex

Bibtex : rorive06

C. Hayot, O. Debeir, P. Van Ham, M. Van Damme, R. Kiss, C. Decaestecker,
Characterization of the activities of actin-affecting drugs on tumor cell migration.
Toxicology and Applied Pharmacology, Vol. 211, 1, pp. 30-40, Feb 2006
Bibtex

Bibtex : hayot06

Dubois F., Yourassowsky C., Monnom O., Legros J. C., Debeir O., Van Ham P., Kiss R., Decaestecker C.,
Digital Holographic Microscopy for the Three-dimensional Dynamic Analysis of In vitro Cancer Cell Migration.
Journal of Biomedical Optics, Vol. 11, 5, pp. 054032-5p., 2006
Bibtex

Bibtex : dubois06

Carleer A.P., Debeir O., Wolff E.,
Assessment of Very High Spatial Resolution Satellite Image Segmentations
Photogrammetric Engineering & Remote Sensing, Vol. 71, 11, pp. 1285–1294, Nov 2005
Bibtex

Bibtex : carleer05

O. Debeir, P. Van Ham, R. Kiss, C. Decaestecker,
Tracking of Migrating Cells Under Phase-Contrast Video Microscopy With Combined Mean-Shift Processes
IEEE Transaction on Medical Imaging, Vol. 24, 6, pp. 697-711, June 2005
Bibtex

Bibtex : debeir05

F. Lefranc, T. Mijatovic, V. Mathieu, S. Rorive, C. Decaestecker, O. Debeir, J. Brotchi, P. Van Ham, I. Salmon, R. Kiss,
Characterization of gastrin-induced proangiogenic effects in vivo in orthotopic u373 experimental human glioblastomas, and in vitro in human umbilical vein endothelial cells (huvec)
Clin Cancer Res, Vol. 10, 24, pp. 8250-65, Dec 2004
Bibtex

Bibtex : lefranc04

O. Debeir, I. Camby, R. Kiss, P. Van Ham, C. Decaestecker,
A Model-Based Approach For Automated In Vitro Cell Tracking And Chemotaxis Analyses
Cytometry, Vol. 60A, 1, pp. 29-40, July 2004
Bibtex

Bibtex : debeir04

D. Haumont, O. Debeir, F. Sillion,
Volumetric Cell-and-Portal Generation
Computer Graphics Forum, Vol. 22, 3, pp. 303-312, Sept 2003
Bibtex

Bibtex : haumont03

O. Debeir, I. Van den Steen, P. Latinne, E. Wolff, Ph. Van Ham,
Spectral, Spatial and Contextual land cover classification using Single and Multiple Classifiers
Photogrammetric Engineering and Remote Sensing (PERS), Vol. 68, 6, pp. 597-605, June 2002
Bibtex

Bibtex : debeir02

Latinne P., Debeir O., Decaestecker C.,
Combining Different Methods and Numbers of Weak Decision Trees
Pattern Analysis and Applications (special issue on Fusion of Multiple Classifiers), Vol. 5, 2, pp. 201-209, 2002
Bibtex

Bibtex : latinne02

O. Debeir, C. Decaestecker, J. L. Pasteels, I. Salmon, R. Kiss, P. Van Ham,
Computer-assisted analysis of epiluminescence microscopy images of pigmented skin lesions
Cytometry, Vol. 37, 4, pp. 255-66, 1999
Bibtex

Bibtex : debeir99

Conferences

Moles Lopez X, Debeir O, Maris C, Roland I, Salmon I, Decaestecker C,
Ki-67 hot-spots detection on glioblastoma tissue sections
Proceedings of the 2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro (ISBI 2010), pp. 149-152, 2010
Bibtex

Bibtex : moleslopez10

Wolff E., Debeir O., Hanson E., Leignel C., Simler C., Beumier C., Warzée N.,
Comparaison et évaluation de méthodes de segmentation avec contrainte en vue d’une classification du bâti et des routes
Proceedings of JIGOT,Informations Géographiques et Observation de la terre, Toulouse (France), Nov 2009
Bibtex

Bibtex : wolff09

Tocino Diaz J. C., Houben Q., Czyz J., Debeir O., Warzée N.,
A camera auto-calibration algorithm for realtime road traffic analysis
VISAPP 2009 : International Conference on Computer Vision Theory and Applications. Lisboa (Portugal), pp. 625-631, Feb 2009
Bibtex

Bibtex : tocino09

Houben Q., Tocino Diaz J. C., Warzée N., Debeir O., Czyz J.,
A multi-features stereo vision system for road traffic analysis
VISAPP 2009 : International Conference on Computer Vision Theory and Applications. Lisboa (Portugal), pp. 554-559, Feb 2009
Bibtex

Bibtex : houben09

O. Debeir, H. Atoui, Ch. Simler, N. Warzée, E. Wolff,
Weakened watershed assembly for remote sensing image segmentation and change detection
Proceedings of VISAPP, pp. 129-134, Lisboa (Portugal), Feb 2009
Bibtex

Bibtex : debeir09a

Q. Houben, J. Czyz, J.C. Tocino Diaz , N. Warzée, O. Debeir,
Feature-based stereo vision using smart cameras for traffic surveillance.
Proceedings of the 7th International Conference on Computer Vision Systems:Computer vision systems (ICVS 2009), pp. 144-153, 2009
Bibtex

Bibtex : houben09a
Note : Lecture Notes in Computer Science

C.Simler, Ch. Beumier, Ch. Leignel, O. Debeir, E. Wolff,
THE USE OF ORFEO TOOLBOX IN THE CONTEXT OF MAP UPDATING
IEEE International Geoscience & Remote Sensing Symposium, Cape Town, South Africa, 2009
Bibtex

Bibtex : simler09

Perez-Careta E., Torres-Cisneros M., Debeir O., Sanchez-Mondragon J., Avina-Cervantes J.G., Ibarra-Manzano O.G., May-Arrioja D., Perez-Pantoja E., Negrete-Romero G.,
Cell tracking by normalized cross-correlation with image processing
IEEE-LEOS Summer Topical Meetings, 2008 Digest of the, pp. 43-44, July 2008
Bibtex

Bibtex : debeir08c

Perez-Careta E., Torres-Cisneros M., Avina-Cervantes J. G., Debeir O., Ibarra-Manzano O. G., Aguilera-Gomez E., Perez-Pantoja E., Negrete-Romero G.,
Cell recognition and tracking using nonlinear cross-correlation
IEEE/LEOS Summer Topical Meetings, 2008 Digest of the, pp. 45-46, 2008
Bibtex

Bibtex : perezcareta08
Abstract : In this work we present a computational cell tracking task using nonlinear filtering joint with cross correlation technique. Nonlinear filtering technique increase tracking robustness respect suddenly shape and size cell changes.

Perez-Careta E., Avina-Cervantes G., Debeir O., Sanchez-Mondragon J. J., Torres-Cisneros M.,
Cells Tracking by Snakes
Medical Physics, Vol. 1032, pp. 124-128, 2008
Bibtex

Bibtex : 2008aipc.1032..124p

O. Debeir, I. Adanja, N. Warzée, P. Van Ham, C. Decaestecker,
Phase contrast image segmentation by weak watershed transform assembly
Proceedings of 5th IEEE International Symposium on Biomedical Imaging : From Nano to Macro (ISBI), pp. 724-727, 2008
Bibtex

Bibtex : debeir08d

O. Debeir, R. Van Ginckel, I. Adanja, F. Darro, R. Kiss, C. Decaestecker,
High throughput characterization of anti-cancer compounds by means of cellular imaging and automatic image analysis.
2007 AACR Annual Meeting in Los Angeles, CA, Apr 2007
Bibtex

Bibtex : debeir07

P. Dunham, O. Debeir, N. Warzée, M. Groenen, J. Rosoux,
Documentation of the El Castillo (Puente Viesgo) cave using 3D scanning
Virtual Retrospect 2007 : Archéologie & Réalité Virtuelle, 2007
Bibtex

Bibtex : dunham07a

Perez-Careta E., Avina-Cervantes J. G., Debeir O., Sanchez-Mondragon J., May-Arrioja D., Torres-Cisneros M.,
Image Processing for in Vitro Cell Tracking
IV Latin American Congress on Biomedical Engineering 2007, Bioengineering Solutions for Latin America Health, pp. 1148-1151, 2007
Bibtex

Bibtex : perez07
Abstract : In this paper, we propose an image processing method able to detect cells trough in vitro phase-contrast video microscopy. Bodies of the cells and image background are very similar; it does not allow having a good performance of tracking process. The proposed method normalizes original image to obtain better object-background contrast, image is equalized to highlight the object to be tracked, and image is threshold in order to obtain a better object-background contrast. Gray Level Morphological Gradient is applied to obtain more defined contours in the areas surrounded by Halos. Dilatation and Erosion were combined to achieve this goal. A subtraction process was applied after dilation of image to obtain borders.

O. Debeir, I. Adanja, R. Kiss, C. Decaestecker,
Automatic in vitro cell division characterization by automatic image sequence analysis.
Belgian Day on Biomedical Engineering - IEEE Benelux EMBS Symposium. Brussels 7-8 December 2006, Dec 2006
Bibtex

Bibtex : debeir06p2

Mundeleer L., Wikler D., Lucidi V., Leloup T., Debeir O., Donckier V., Warzée N.,
Computer assisted needle positioning for liver tumor radiofrequency ablation (RFA)
In proceedings First Symposium of the IEEE/EMBS Benelux Chapter, pp. 263-266, Dec 2006
Bibtex

Bibtex : mundeldec06
Abstract : Radio frequency ablation (RFA) is a minimally invasive treatment for either hepatocellular carcinoma or metastasis liver carcinoma. In order to resect large lesions, the surgeon has to perform multiple time-consuming destruction cycles and reposition the RFA needle for each of them. The critical step in handling a successful ablation and preventing local recurrence is the correct positioning of the needle. For small tumors, the surgeon places the middle of the active needle tip in the center of the tumor under intra-operative ultrasound guidance. When one application is not enough to cover the entire tumor, the surgeon needs to repeat the treatment after repositioning of the needle, but US guidance is obstructed by the opacity stemming from the first RFA application. In this case the surgeon can only rely on anatomical knowledge and the repositioning of the RFA needle becomes a subjective task limiting the treatment accuracy. We have developed a computer assisted surgery guidance application for this repositioning procedure. Our software application handles the complete process from preoperative image analysis to tool tracking in the operating room. Our framework is mostly used for this RFA procedure, but is also suitable for any other medical or surgery application.

F. Ambriz-Colin, M. Torres-Cisneros, J.G. Avina-Cervantes, J.E. Saavedra-Martinez, O. Debeir, J.J. Sanchez-Mondragon,
Detection of Biological Cells in Phase-Contrast Microscopy Images.
Fifth Mexican International Conference on Artificial Intelligence (MICAI'06), Nov 2006
Bibtex

Bibtex : ambrizcolin06

V. Mégalizzi, V. Mathieu, T. Mijatovic, P. Gailly, O. Debeir, M. Van Damme, C. Decaestecker, Y. Kondo, R. Kiss, F. Lefranc,
4-IBP, A SIGMA1 RECEPTOR AGONIST, DECREASES IN VITRO THE MIGRATION OF HUMAN CANCER CELLS, INCLUDING GLIOBLASTOMA CELLS, AND SENSITIZES THEM TO THE CYTOTOXIC INSULTS OF PRO-APOPTOTIC AND PRO-AUTOPHAGIC DRUGS
Autumn Meeting 2006 on Cytoskeleton and Cellular Imaging of BSCDB. Ghent, October 14th, Oct 2006
Bibtex

Bibtex : megalizzi06p1

O. Debeir, R. Kiss, C. Decaestecker,
Cell division characterization by automatic cell tracking and cell lineage reconstruction.
Autumn Meeting 2006 on Cytoskeleton and Cellular Imaging of BSCDB. Ghent, October 14th, Oct 2006
Bibtex

Bibtex : debeir06p1

D. Unay, O. Debeir, B. Gosselin,
Apple Stem and Calyx Recognition by Decision Trees
IASTED Visualization, Imaging and Image Processing Conference (VIIP 2006), Palma de Mallorca, Spain, 2006
Bibtex

Bibtex : unay06a

T. Leloup, W. El Kazzi, O. Debeir, F. Schuind, N. Warzée,
Automatic fluoroscopic Image Calibration for Traumatology Intervention Guidance.
Proc. of the EUROCON 2005. Serbia and Montenegro, Belgrade, November 22-24, 2005, pp. 374-377, Nov 2005
Bibtex

Bibtex : leloup05

O. Debeir, C. Decaestecker,
Mitotic Tree Construction by Computer In Vitro Cell Tracking : a Tool for Proliferation and Motility Features Extraction.
Proc. of the EUROCON 2005. Serbia and Montenegro, Belgrade, November 22-24, 2005, Nov 2005
Bibtex

Bibtex : tree05

C. Hayot, O. Debeir, P. Van Ham, M. Van Damme, R. Kiss, C. Decaestecker,
Characterization of the anti-tumor cell migration activities of actin-affecting drugs.
CELL MIGRATION IN CANCER AND IMMUNITY Joint Spring Meeting of the Belgian Society for Cell and Developmental Biology, Brussels, May 27-28, 2005, May 2005
Bibtex

Bibtex : hayot05b

S. Servotte, I. Camby, O. Debeir, C. Deroanne, C-M. Lapière, R. Kiss, B. Nusgens, C. Decaestecker,
Neurotensin activates rac1 and cdc42, but not rhoa, in human U373 glioblastoma cells, and modifies their migratory patterns.
CELL MIGRATION IN CANCER AND IMMUNITY Joint Spring Meeting of the Belgian Society for Cell and Developmental Biology, Brussels, May 27-28, 2005, May 2005
Bibtex

Bibtex : servotte05b

O. Debeir, P. Van Ham, R. Kiss, C. Decaestecker,
Tracking of migrating cells under phase-contrast video microscopy with combined mean-shift processes.
CELL MIGRATION IN CANCER AND IMMUNITY Joint Spring Meeting of the Belgian Society for Cell and Developmental Biology, Brussels, May 27-28, 2005, May 2005
Bibtex

Bibtex : debeir05d

A. Carleer, O. Debeir, E. Wolff,
Comparison of very high spatial resolution satellite image segmentations.
Proceedings of SPIE - Volume 5238 Image and Signal Processing for Remote Sensing IX, Feb 2004
Bibtex

Bibtex : carleer04

I. Van den Steen, E. Wolff, O. Debeir, P. Van Ham, P. Latinne,
Amélioration de l'interprétation numérique de l'occupation du sol.
23e Symposium canadien sur la télédétection, Congrès de l'Association québécoise de télédétection, Québec, Canada. La télédétection au troisième millénaire : Du global au local, 2001
Bibtex

Bibtex : vandensteen01remote

P. Latinne, O. Debeir, C. Decaestecker,
Limiting the Number of Trees in Random Forests.
Multiple Classifier Systems, Vol. 2096, pp. 178-187, 2001
Bibtex

Bibtex : latinne01limit

O. Debeir, P. Latinne, I. Van den Steen,
Remote Sensing Classification of Spectral, Spatial and Contextual Data Using Multiple Classifier Systems
Proc. of the 8th European Congress of Stereology and Image Analysis ECS-IA'2001, 2001
Bibtex

Bibtex : debeir01remote

P. Latinne, O. Debeir, C. Decaestecker,
Different Ways of Weakening Decision Trees and Their Impact on Classification Accuracy of DT Combination.
Multiple Classifier Systems, Vol. 1857, pp. 200-209, 2000
Bibtex

Bibtex : latinne00weak

P. Latinne, O. Debeir, C. Decaestecker,
Mixing Bagging and Multiple Feature Subsets to Improve Classification Accuracy of Decision Tree Combination.
BENELEARN 2000, Tenth Belgian-Dutch Conference on Machine Learning, Tilburg University, Netherlands, December 13 2000., 2000
Bibtex

Bibtex : latinne00mixing

O. Debeir, Philippe Van Ham,
Pigmented Skin Lesion cartography by supervised image segmentation : Pixel vs Region classification.
International Symposium on Pattern Recognition, 1999
Bibtex

Bibtex : debeir99

Debeir O., Goldscmidt D, Kraft T, Kiss R, Van Ham P,
Skin Lesions in ELM Color Images.
9th International Conference on Diagnostic Quantitative Pathology, October 26 - 28, 1995, Congress Center, German Cancer Research Center, Heidelberg, Germany, Oct 1995
Bibtex

Bibtex : debeir95

Books chapters

Debeir O., Adanja I., Kiss R., Decaestecker C.,
Models of cancer cell migration and cellular imaging and analysis
The Motile Actin System in Health and Disease, pp. 123-156, Kerala (India), 2008
Bibtex

Bibtex : debeir08b

Thesis

Debeir O. - Segmentation supervisée d'image Ph.D. Thesis, Université Libre de Bruxelles , 50, av. F.D.Roosevelt 1050 Bruxelles, Belgique, apr 2002 Bibtex Author : Debeir O. Title : Segmentation supervisée d'image In : Ph.D. Thesis, Université Libre de Bruxelles - Address : 50, av. F.D.Roosevelt 1050 Bruxelles, Belgique Date : apr 2002 edit Debeir O. - DEA : Segmentation d'images par classification supervisée de régions DEA, Université Libre de Bruxelles , 50, av. F.D.Roosevelt 1050 Bruxelles, Belgique,2001 Bibtex Author : Debeir O. Title : DEA : Segmentation d'images par classification supervisée de régions In : DEA, Université Libre de Bruxelles - Address : 50, av. F.D.Roosevelt 1050 Bruxelles, Belgique Date : 2001 edit

Project and stage

Acquisition et reconstruction 3D à travers une fibre optique pour des applications endoscopiques (MFE Biomed 5)
Etudiants : Vincent HEYMANS
Promoteurs : Olivier DEBEIR

Identification de vaisseaux sanguins au sein de coupes histologiques par apprentissage et analyse d'images (MFE Biomed 5)
Etudiants : Frédéric MOREL
Promoteurs : Christine DECAESTECKER, Olivier DEBEIR

Improvement of Image Segmentation Based on Statistical Shape and Intensity Models (MFE Biomed 5)
Etudiants : Maximilien RENARD
Promoteurs : Olivier DEBEIR

Mesures de paramètres morphologiques de neurones à partir d'images obtenues par microscopie confocale (MFE Biomed 5)
Etudiants : Adrien FOUCART
Promoteurs : Olivier DEBEIR, David GALL

Analyse morphologique de cellules dans une séquence (Projet Informatique 4)
Etudiants : Geoffroy LOUMAYE
Promoteurs : Olivier DEBEIR

Calibration d'un système d'acquisition 3D (Projet Informatique 4)
Etudiants : Taheri Abdeslam BAKKALI
Promoteurs : Olivier DEBEIR

Détection de mitoses au sein d'une séquence acquise par microscopie à contraste de phase (Projet EM 4)
Etudiants : Aibek VAN DEN ACKERVEKEN
Promoteurs : Patrick HENDRIC, Olivier DEBEIR

Quantification de la fluorescence de cellules marquées à l'aide d'un procédé d'immunofluorescence (Projet Biomed 4)
Etudiants : Gwennaëlle MARIN
Promoteurs : Olivier DEBEIR, Xavier MOLES LOPEZ

Réalisation d'un scanner tomographique (Projet Biomed 2)
Etudiants : Aurore DE BECKER, Jorge GARCIA XIMENEZ, Nathalie MAJCHERCZYK, Bruno PRZETAKIEWICZ, Robin PUTMAN, roger TILMANS, Dimitri ZVENY
Promoteurs : Olivier DEBEIR, Laurent LONYS

Segmentation de noyaux soumis à un procédé d'immunofluorescence (Projet Biomed 4)
Etudiants : Barbara DEMOUTIER
Promoteurs : Olivier DEBEIR

Développement d'un logiciel de traitement d'images pour l'analyse quantitative de tâches hyperpigmentées sur un visage éclairé par de la lumière blanche (MFE Biomed 5)
Etudiants : Juliette ROSTAING
Promoteurs : Olivier DEBEIR, Dr HEENEN, Dr VEREECKEN

Conception et réalisation d'un robot d'aide aux personnes âgées dans la gestion ou le tri de leurs médicaments (Projet biomed 2)
Etudiants : Gaëlle COUTURIAUX, Damien DASNOY-SUMELL, Antoine DEJONCKHEERE, Robin DEVOOGHT, Nancy GARCIA FERNANDEZ, Hélène GOSSELIN, Thibault NUTTIN, Jocelyn WILLAIME
Promoteurs : Quentin LURKIN, Olivier DEBEIR

Evaluation automatique de la surface recolonisée par des cellules cultivées in vitro lors d'une expérience de wound healing (Projet Biomed 4)
Etudiants : Juliette ROSTAING
Promoteurs : Olivier DEBEIR

Evaluation de l'éloignement d'outils en endoscopie flexible interventionnelle (Projet Biomed 4)
Etudiants : Vincent HEYMANS, Benjamin HORSMANS
Promoteurs : Olivier DEBEIR

Recalage de coupes sériées acquises par microscopie optique (Projet Biomed 4)
Etudiants : Fabian MARTINO, Frédéric MOREL
Promoteurs : Olivier DEBEIR

Développement d'une plate-forme d'analyse d'image dédiée à la biologie cellulaire. (Stage 2)
Etudiants : Mohamed ELHOUDERI
Promoteurs : Olivier DEBEIR

Développement d'une plate-forme d'analyse d'images sous Python. (Stage)
Etudiants : Louis BREMAND
Promoteurs : Olivier DEBEIR, Ivan ADANJA, Christine DECAESTECKER, Nadine WARZEE

Bathyscaphe (Projet BA 1)
Etudiants : Laurent PIELTAIN (Chef d'équipe de 6 étudiants)
Promoteurs : Olivier DEBEIR

Conception d'un automate manipulateur de boîtes à essais (Projet 2)
Etudiants : Patrick AHORUKOMEYE, Alexandre BALON-PERIN, Cécile CAILLOL, Anthony COYETTE, Alexandre DOMB, Cédric DUMOULIN, Stephan HAHN
Promoteurs : Olivier DEBEIR

Conception d'une table multi-touch (Projet 3)
Etudiants : Sothy CHAU, Willy-Dawid KHOV, Allan ROBERT
Promoteurs : Olivier DEBEIR

Le grand plongeon (Projet 1)
Etudiants : Xavier DUFOUR, Cyril MORTREU, Valerio CORDA, Marc SAINANEE, Maxime FONTEYNE, Nicolas HOLLANDER, Stevnen De Lobel
Promoteurs : Olivier DEBEIR

Mise en place d'une base de données de "Tissue Micro Array" (Projet Info 4)
Etudiants : Abdellah STITOU
Promoteurs : Xavier MOLEZ LOPEZ, Olivier DEBEIR

Réalisation d'un écran tactile multi-touch basé sur un module laser plan retro-éclairé et l'analyse d'image (Projet Info 3)
Etudiants : Sothy CHAU , Willy David KHOV , Allan ROBERT
Promoteurs : Olivier DEBEIR, Laurent ENGELS

Réalisation d'un lutrin virtuel interactif (Projet Info 4)
Etudiants : Anne-Sophie FEYAERTS
Promoteurs : Olivier DEBEIR, Frédéric DE GROEF

Robot manipulateur de boites de Petri (Projet BA 2)
Etudiants : Aurélie COLLIER , Bruno ROCHA , Ludovic LAFFINEUR , Alexandre DESCY, Thomas GEURY , Sébastien DASNOY-SUMELL
Promoteurs : Olivier DEBEIR, Laurent LONYS

Robot pipeteur (Projet BA 2)
Etudiants : Anthony COYETTE , Cécile CAILLOL , Patrick AHORUKOMEYE , Stephan HAHN , Alexandre BALON-PERIN , Cédric DUMOULIN , Alexandre DOMB
Promoteurs : Olivier DEBEIR

Réalisation d'un robot manipulateur de boîtes de Petri (Rapport 2)
Etudiants : Aurélie COLLIER, Sébastien DASNOY-SUMELL, Alexandre DESCY, Thomas GEURY, Ludovic LAFFINEUR, Bruno ROCHA
Promoteurs : Olivier DEBEIR, Laurent LONYS

Elaboration de descripteurs dynamiques de changement de forme d'objet 2D et leur application aux objets biologiques (MFE Biomed 5)
Etudiants : Aboubacar DIOP
Promoteurs : Olivier DEBEIR , Christine DECAESTECKER

Réalisation d'une table multi-touch (Projet 3)
Etudiants : Thibault DELEU, Anne-sophie FEYAERTS, Andreï NOVIKOV-DANEL
Promoteurs : Olivier DEBEIR

Système de navigation de séquences d’images 3D et recherche de plan focal (Projet Biomed 3)
Etudiants : Yassine KABBAJ
Promoteurs : Olivier DEBEIR, Ivan ADANJA

Analyse de la qualité d'image d'une empreinte digitale (MFE Informatique 5)
Etudiants : Yoppy Americo SATRIANTO
Promoteurs : Thierry LELOUP, Olivier DEBEIR, Nadine WARZEE

Elaboration de protocoles pour une quantification standardisée de marqueurs immunohistochimiques par analyse d’images digitales (MFE Biomed 5)
Etudiants : Younes JOURANI
Promoteurs : Olivier DEBEIR , Isabelle SALMON , Christine DECAESTECKER

Modèle 3D à partir d'acquisitions microscopiques sériées (Projet Télécommunications 5)
Etudiants : Alexandre VANDENBUSSCHE
Promoteurs : Olivier DEBEIR

Segmentation d'image par marche aléatoire (Projet 4)
Etudiants : Benjamin POULAIN
Promoteurs : Olivier DEBEIR

Optimisation d'une tourelle laser déterminant la position d'un robot (Projet Informatique 3)
Etudiants : Frédérick DEGROOF, Xavier SAND, Abdellah STITOU
Promoteurs : Olivier DEBEIR